INSIGHTS INTO DETERMINANTS OF SPLEEN INJURY IN SICKLE CELL ANEMIA

Insights into determinants of spleen injury in sickle cell anemia

Abstract: Spleen dysfunction is central to morbidity and mortality in children with sickle cell anemia (SCA).The initiation and determinants of spleen injury, including acute splenic sequestration (ASS) have not been established.We investigated splenic function longitudinally in a cohort of 57 infants with SCA enrolled at 3 to 6 months of age and f

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Procedural Optimization Models for Multiobjective Flexible JSSP

The most challenging issues related to manufacturing efficiency occur if the jobs to be sched-uled are structurally different, if these jobs allow flexible routings on the equipments and mul-tiple objectives are required.This framework, called Multi-objective Regular Flexible Job Shop Scheduling Problems (MOFJSSP), applicable to many real processes

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